(R)-Betaxolol hydrochloride | C18H30ClNO3 | CID 12937007 - structure, chemical names, physical and chemical properties, classification, patents, literature Betaxolol (Systemic) Class: beta-Adrenergic Blocking Agents. VA Class: CV100. Chemical Name: 2-Propanol, 1- (4- (2- (cyclopropylmethoxy)ethyl)phenoxy)-3- ( (1-methylethyl) amino)-, hydrochloride. Molecular Formula: C 18 H 29 NO 3 •ClH. Betaxolol hydrochloride is a water-soluble white crystalline powder with a molecular formula of C 18 H 29 NO 3 •HCl and a molecular weight of 343.9. It is freely soluble in water, ethanol, chloroform, and methanol, and has a pKa of 9.4. Betaxolol Hydrochloride is the hydrochloride salt form of betaxolol, a beta-1-selective adrenergic receptor antagonist without intrinsic sympathomimetic activity. Betaxolol hydrochloride acts on the heart and circulatory system and decreases cardiac contractility and rate, thereby reducing cardiac output. Common beta-blockers include timolol maleate, betaxolol hydrochloride, carteolol hydrochloride, levobunolol hydrochloride and metipranolol. Timolol is often used together with another agent (combination drugs), e.g. timolol and brimonidine, timolol and dorzolamide, timolol and latanoprost. Betaxolol Hydrochloride Ophthalmic Solution contains Betaxolol hydrochloride, a cardioselective beta-adrenergic receptor blocking agent, in a sterile isotonic solution. Betaxolol hydrochloride is a white, crystalline powder, soluble in water, with a molecular weight of 343.89. The chemical structure is presented below: Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.;Target: Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergic receptor blocking agent. Betaxolol (5 mg/kg via i.p. injection) 5 Citations for Betaxolol hydrochloride. Citations are publications that use Tocris products. Selected citations for Betaxolol hydrochloride include: Schutsky et al (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. Betaxolol Hydrochloride Ophthalmic Solution 0.5% as base Sterile . DESCRIPTION. Betaxolol Hydrochloride Ophthalmic Solution contains betaxolol hydrochloride, a cardioselective beta-adrenergic receptor blocking agent, in a sterile isotonic solution. Betaxolol hydrochloride is a white, crystalline powder, soluble in water, with a molecular weight of 343.89. Betaxolol/Betaxolol Hydrochloride/Kerlone Oral Tab: 10mg, 20mg Betoptic S Ophthalmic Susp: 0.25%. DOSAGE & INDICATIONS. For the treatment of hypertension. Oral dosage. Adults. Initially, 10 mg PO once daily, either alone or added to diuretic therapy.
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